The H1155 cell line, also known as NCI-H1155, is a human non-small cell lung cancer (NSCLC) cell line derived from a patient with lung adenocarcinoma. It is widely used in cancer research, particularly in the study of lung cancer biology, drug resistance, and the development of novel therapeutic strategies.
The H1155 cell line has been employed in various research applications, such as:
- Investigating the molecular mechanisms underlying lung cancer development and progression.
- Studying the cellular response to chemotherapeutic agents and targeted therapies, as well as developing strategies for overcoming drug resistance.
- Evaluating the efficacy of novel anticancer therapeutics and treatment strategies in vitro before testing them in in vivo models.
- Identifying and validating potential therapeutic targets and biomarkers for lung cancer.
The use of the H1155 cell line, along with other lung cancer cell lines, has contributed significantly to advancing our understanding of lung cancer biology and has aided in the development of more effective treatment options for patients.